When it comes to drug therapy, there is no one right dose for all patients. Each patient is unique and deserves individual treatments tailored specifically for them. Precision dosing has been shown to have significant benefits by improving patient outcomes, reducing drug failure, avoiding adverse drug reactions, and lowering overall healthcare costs. Understand the benefits of precision dosing and how our web-based application, iDose, can improve your patient outcomes.
Improved patient outcomes
Biomarkers are used as an indication that a biological process in the body has happened or is ongoing. According to this study, these measures can be used to characterize the body’s response to therapeutic intervention and represent a valuable avenue for precision dosing. Several biomarkers are commonly used for facilitating dose individualization and have been associated with improved patient outcomes.
Other analyses have suggested improved patient outcomes from precision dosing include:
- When managed with pharmacokinetic consultation and individualized dosing, patients in the severely ill group should have significantly better drug survival.
- Therapeutic drug monitoring in induction along with dose adjustment also improves response (https://ddw.apprisor.org/epsAbstractDDW.cfm?id=1).
Reduced drug failure
If patients are not receiving the right dose, the results could range from not getting better to feeling worse than before. If a patient receives a more precise, individualized dose, they may see a boost in the drug’s effectiveness against the disease while reducing or eliminating any potential side effects. With iDose, we found that patients under precision dosing regimens get better quicker and stay in remission longer compared to normal dosing patients.
Avoiding adverse drug reactions
In the United States, adverse drug reactions (ADRs) are a leading cause of death and cost billions of dollars in avoidable healthcare costs. According to a study, patients treated using iDose had no increase in ADRs Precision dosing principles help avoid adverse drug reactions that are related to inadequate dosage regimen selection.
Lower healthcare costs
When drug regimens are effectively tailored to each individual, healthcare costs will significantly decrease because there will be an optimized use of limited healthcare resources. The approach of drug dosing with iDose would move clinical practice toward a more patient-centered healthcare system which improves patient outcomes and lowers the total cost of care.
Here are a few findings from our case study utilizing iDose to minimize healthcare costs:
- Utilize the “Refine a Dose” feature of iDose, which keeps the trough concentration constant while altering dose amount and interval
- Consider infusion cost and drug cost relative to the desired trough concentration target
- In the Managing Infliximab Study (Exploratory), the results from 7 patients were reported separately. Cost analysis was reported for 1 CD patient with a 60% cost reduction by increasing the dosing interval from 4 to 7 weeks. The patient was clinically stable with the new dosing regimen.
You can read more about how precision dosing lowers overall healthcare costs while improving patient outcomes in our most recent blog here.
Contact Us
At Baysient, we value the fact that all patients are unique and deserve individual treatments tailored specifically for them, changing as they heal. There is no single dose that is right for all patients. That is why our goal is to provide individualized treatments for patients with improved outcomes at lower costs.
iDose, our cloud-based software, uses Bayesian models, routine lab results, and demographic information to allow physicians to individualize dosing to a specific target trough level. Interested in how iDose can improve your patient outcomes? Schedule a Demo today!
